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Furthermore, mitochondrial membrane potential (m) decline, increased mitochondrial outer membrane permeability and mitochondrial DNA (mtDNA) damage have been identified as key regulatory factors in ferroptosis (10,11)

Therefore, the use of several sub-strains of mice is a strength of this study [49, 50], and suggests that our findings are more likely to generalize to other mouse sub-strains than they would have if the study were conducted in only one strain of mice

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The outlook is especially concerning in China

Semax Semax (Russian: Russian: medication which is used in Eastern Europe for the treatment of a broad range of conditions like brain trauma but predominantly for its claimed nootropic, neuroprotective, and neurorestorative effects

Ebselen is another promising antioxidant that scavenges ROS and mimics glutathione peroxidase [132]