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Both protein level and activity of SIRT1 were higher in WT mice after exenatide treatment, while no obvious change was observed in Sirt1 +/ mice regardless of exenatide treatment (Fig

Studies have indicated that, in human NAFLD patients, increased PARP activity could potentially lead to NAD + depletion and mitochondrial dysfunction 164

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The medication had been prescribed by endocrinologist involved in obesity treatment, with the participants consent and agreement