244 Berberine alleviates diabetes-induced pain by inhibiting transient receptor potential vanilloid 1 (TRPV1) and the PKC pathway, reducing inflammation (Fig
119 As glucagon can bind to GLP-1R, it may also be able to weakly stimulate insulin secretion through the action of this receptor as well as promote apoptotic resistance, proliferation and increased glucose sensing, as all of these effects are associated with GLP-1R activation
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PubMed American Diabetes Association Professional Practice Committee