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Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): major impact on lives of both patients and family members

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This myoglobin can precipitate in the renal tubules, causing acute kidney injury (AKI) and, in extreme cases, irreversible renal failure

doi:10.1007/s11010-013-1869-2

Feeling cold Feeling cold on tirzepatide is widely reported and relates to reduced caloric intake, lower body fat insulation, and metabolic changes from weight loss

However, given the less effective repair and remyelination, access to these treatments will be especially important in older populations and it is essential that the pharmaceutical industry and investigators proactively consider including subgroups of older patients that are traditionally excluded from trials