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[ Hibiscus rosa-sinensis exhibited moderate cytotoxicity in L929 fibroblasts with approximately 76% cell viability at 100 g/mL, while showing minimal toxicity in HaCaT keratinocytes, supporting their selective safety profile for nanotherapeutic research [ Spinacia oleracea -derived CQDs maintained high viability in human mesenchymal stem cells at lower concentrations, and displayed dose-dependent reductions at higher exposure concentrations, indicating their suitability for bioimaging and stem cell-related applications [154]
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