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ADVERSE EFFECTS Some epidemiologic evidence indicates that long-term use of acetaminophen is associated with an increased risk of renal dysfunction .M Although therapeutic doses of acetaminophen are remarkably nontoxic, the ingestion of 20 to 30 tablets is sufficient to cause life-threatening hepatotoxicity .

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Or so its popularity suggests: The diabetes medication, which can lead to loss of up to 15% of body weight, is in such a demand-generated shortage that Novo Nordisk decided to pause Wegovy advertising