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[DOI] [PMC free article] [PubMed] [Google Scholar] 529
Canadian sites are active in ongoing Phase 3 trials
10.1016/j.ocarto.2022.100255
Other risk factors associated with a persons occupation, including lack of sleep and night-shift work, have also been shown to increase the risk of developing certain types of cancers and other chronic diseases, including diabetes and obesity (344)McDermott JE, et al
At standard doses (325650 mg every 46 hours, max 3,000 mg/day), it avoids NSAID-GI interactions and does not increase cardiovascular or renal risk
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