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Correlations of acyl-carnitines and clinical outcomes The correlation analysis of acyl-carnitine concentrations was calculated using Spearman correlation analysis, considering subjects both before and after clinical treatment and healthy controls

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Moreover, highly selective small molecule inhibitors of USP14 (IU1 and derivatives), exhibit the capacity to increase the activity of the 26S 15,19 , and show affinities towards USP14 compatible with their use in a chimera design 15,19,20

Keenan K, Hipwell A, McAloon R, Hoffmann A, Mohanty A, Magee K

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(2018) 10:e2098