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Zhang C, Hu JJ, Xia M, Boini KM, C Brimson, PL Li

Nonpharmacologic measures for treating osteoarthritis include joint protection and splinting, physiotherapy, orthotic prostheses to support the feet, and joint replacement surgery

Most patients find side effects manageable and temporary compared to the appetite-suppressing benefits

Moreover, the cardiovascular benefits of Semaglutide have sparked intrigue within the scientific community

To the extent a particular GLP-1 drug (for instance, tirzepatide or semaglutide) is removed from FDAs shortage list, and to the extent compounders and telehealth companies continue making and selling copies, they are subject to enforcement by FDA and, courts have held, civil liability to the drug company who owns the patent

Nature 387 , 903908 (1997)