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GIP/GLP-1) have shown reductions exceeding 20% in early trials [28,29,30]

In addition to GLP-1R, the peptide itself appears to be important for this interaction, as the increased levels of GLP-1 after DPP-IV inhibition (with sitagliptin) reduce nicotine consumption in male mice (Tuesta et al., 2017)

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All participants has a CD4+ T lymphocyte count greater than 100 cells/mm^3, as well as HIV-1 RNA less than 10,000 copies/mL