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Typically occurring between ages 45 and 55, perimenopause transition is characterized by fluctuating estrogen levels and declining ovarian function that initiate a cascade of physiological and psychological changes that extend far beyond reproductive health

If a patient takes more medication than is recommended, significant side effects such as renal failure or blood poisoning may appear

Severe GI side effects that prevent you from maintaining adequate hydration despite your best efforts

89.39% 15.37%, n = 6 and 8 respectively

10.1038/nrc2544 26 BykovV

In fact I was a little apprehensive about GI side effects as saw that during oral sema RCT