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Second, given that the activation of GSR and TXNRD1 are involved in ROS elimination, if the LCS3-triggered lethality of VRK2-KO PC cells could be attributed to inhibiting the activity of both GSR and TXNRD1, then the level of ROS generated by LCS3 should have been much higher than those produced by the treatment of the TXNRD1 inhibitor auranofin

Nat Rev Endocrinol (2019) 15:47988

If you simultaneously reduce dose, change injection timing, and switch sources, you will not know which change helped

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Traditional oral Glutathione has limited bioavailability because it breaks down in the digestive system