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Conversely, some people experience loose stools or diarrhea , particularly in the first days after injection

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Expert Consensus on Transdermal Weight Loss Patches: Transdermal delivery is an established pharmaceutical technology used for certain medications, but whether a compound works through the skin depends on the molecule's characteristics (size, solubility, formulation) and the delivery system used

It is noteworthy that exendin-4 (Ex-4), a peptide derived from the saliva of the American Gila monster, exhibits pharmacological functions similar to those of GLP-1 and is resistant to DPP-4 degradation

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Amir LR, Li G, Schoenmaker T, Everts V, Bronckers AL