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They stated that reducing ratings for nearly 20 percent of hospitals is excessive relative to the identified issue and supported alternative statistical methods to more precisely identify poor performers or outliers

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CDC summarizes USP guidance: date an opened multi-dose vial at first puncture and discard it within 28 days unless the manufacturer states another opened-vial date. The dose count and 28-day window together require three vials for the 12-week protocol

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