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Joint aspiration for laboratory analysis may ultimately be required, as it can identify urate crystals, and Gram stain or culture can confirm/exclude the presence of infection

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We don't use a one-size-fits-all method because bodies don't work that way

Adding less than 0.5 mL to any vial makes accurate dosing extremely difficult with standard syringes

It is not a magic bullet and it will not do away with surgery or fix structural issues such as bone-on-bone arthritis, or reverse severe deformities