glp-1 shits A diabetes drug. Then a weight-loss drug. Then a global blockbuster. Here's how GLP-1s went from helping manage blood sugar to becoming one of medicine's biggest stories. [GLP-1, Ozempic, Wegovy, Mounjaro, diabetes GLP-1 Weight Loss Journey: From

Exenatide, a synthetic version of exendin-4 produced industrially, was the first GLP-1RA approved for the market [exenatide twice daily (EX-BID)], followed by a long-acting formulation that improved the delivery system [exenatide once a week (EX-QW)]

(BD) Body-weight change during Orforglipron treatment

Oral semaglutide at a dose of 25 mg in adults with overweight or obesity

Currently, Hers offers a range of GLP-1s in the form of injectables and oral medications, and its available in all states

Annual sales of GLP-1 based drugs are expected to overtake the US$ 100 billion mark by 2029 (Park)

When tirzepatide was on the FDA drug shortage list, Section 503A of the Federal Food, Drug, and Cosmetic Act allowed licensed compounding pharmacies to produce compounded versions