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Technical reviews, systematic reviews, meta-analyses, and clinical guidelines on CVS, as well as information from observational studies, case series, case reports, and intervention studies on patients with CVS, were included in the search

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The safety, tolerability, and pharmacokinetics of PF-06882961 were evaluated in a first-in-human, Phase 1, randomized, double-blind, placebo-controlled, single ascending dose study in healthy adult participants

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No research-use label or wording that hints at human use

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