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Parameters to monitor Serum electrolytes (especially creatinine and potassium) Symptoms of angioedema BP Symptoms of hypotension CBC (especially with captopril and enalapril) for neutropenia, which is more common in patients with preexisting renal impairment Cough Urinary proteins Direct Renin Inhibitors See Table 12-16 for a list of direct renin inhibitors, their usual dosage range, and adverse effects associated with these medications

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Severe gastroparesis or other serious gastrointestinal disorders, because tirzepatide slows stomach emptying, which can aggravate these conditions

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