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250,251 These recent studies, which exploit new technologies, reached conclusions that are reminiscent of early studies 249 that separated carcinogenesis into initiation and promotion stages and reinforce the notion that avoidance of promotion is an important approach in cancer prevention

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Interestingly, while GLP-1-expressing NTS neurons also project to the ventral striatum [102] and administration of exendin-4 into this brain region reduces food intake and the motivation to obtain a food reward [100, 102], this treatment does not affect ventral striatal dopamine release [103]