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In addition to functioning as a purification tag, GST acts as a chaperone for the attached protein, promoting its correct folding, as well as preventing it from becoming aggregated in inclusion bodies when expressed in bacteria

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PMID 36498958

It may only be considered off-label under specialist supervision when type 2 diabetes coexists with PCOS, as it can improve insulin resistance

The maximum FDA-approved dose is 15 mg once weekly for both Mounjaro and Zepbound

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