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The insulin-independent effects on glycogen synthesis are mediated through GLP-1 signaling through phosphoinositide 3-kinase (PI3K), AKT, PKC, and protein phosphatase-1 (PP-1) activity, but the interplay between these enzymes is not currently fully understood in GLP-1-mediated glycogen metabolism [88]

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The flip side they call the Prime metabotype: high weight loss with preserved lean mass