(2013) 5:205rv1
Interactions of Mediterranean diet, obesity, polypharmacy, depression and systemic inflammation with frailty status
The resulting reactive aldehydes, such as 4-hydroxy-2-nonenal (4-HNE) and malondialdehyde (MDA), not only form adducts with DNA and proteins but also act as secondary messengers that modulate signaling and cell death [41, 42]
Neuroscience and Biobehavioral Reviews via PubMed (PMID 29733881), 2018 The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases (review note the authors were affiliated with M3 Biotechnology, a company commercializing dihexa)
Don't immediately stack strong acids (glycolic, retinol) over it
Bacterial lipopolysaccharide inhibits free thiamin uptake along the intestinal tract via interference with membrane expression of thiamin transporters 1 and 2