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Results Stapled peptide design and structureactivity relationships To identify inhibitors of the FAT domain of FAK, we employed the hydrocarbon-based stapling approach in the design of peptide analogs with drug-like features such as increased stability, proteolytic resistance, binding affinity, cell permeability, and DMPK properties

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10.1074/jbc.272.33.20811 87 NinomiyaM.HaradaN.ShiotaniS.HiroshigeS.MinagawaR.SoejimaY.et al (2003)

Acknowledgements This work was supported by the National Innovation of Science and Technology-2030 (Program of Brain Science and Brain-Inspired Intelligence Technology, Grant 2021ZD0204002)

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