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Standard community protocols run tirzepatide alone for the first 8 weeks (2.5 5 mg/week) to confirm GI tolerance, then add cagrilintide at 0.25 mg/week starting Week 9

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However, it remains a preclinical compound: unapproved by the FDA, prohibited under WADAs Schedule 0 category, and without a single completed, published human trial

Research interest has grown significantly as scientists explore NNMT's role in metabolic regulation, adipogenesis, and energy homeostasis