On the other hand, ferroptosis inhibitors can also alleviate the nerve cell death caused by iron excess, which indicates that ferroptosis is directly involved in ischemic stroke
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Hertel J, et al
Upon initiating therapy, the endocrinologist ensures appropriate dose titration to minimise GI side effects, provides education on injection technique and timing, and establishes therapeutic goals, such as glycaemic control, weight reduction, and improvement in cardiometabolic risk
These agents mitigate muscle atrophy by downregulating atrophy-related factors (myostatin, MuRF1, MAFbx) and upregulating myogenic transcription factors (MyoD, MyoG) via PKA/Akt/mTOR signaling
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