For individuals with severe B12 deficiency (especially those with anaemia or neurological symptoms), some might start to feel an improvement in their energy levels within a few days to a week
Whether you have insurance, whether your plan covers semaglutide for weight loss, and even where you get your prescription filled can all make a big difference
Late responders typically achieve 25-35 pounds of loss, still clinically meaningful but below trial averages
Good options that are typically well-tolerated with IBS include: Chicken and turkey (plain, not heavily spiced) Fish, particularly oily fish like salmon Eggs (often well-tolerated even with IBS) Tofu and tempeh (some people with IBS tolerate these better than beans) Greek yoghurt (if you tolerate dairy) Low-FODMAP vegetables If you follow a low-FODMAP approach for IBS, focus on vegetables that are less likely to trigger symptoms: Carrots, courgettes, and aubergines Spinach and other leafy greens Bell peppers and tomatoes Green beans and cucumber Complex carbohydrates Choose carbohydrates that provide sustained energy without triggering IBS symptoms: White or basmati rice (often better tolerated than wholegrain for IBS) Oats (if tolerated) Potatoes and sweet potatoes Sourdough bread (the fermentation process reduces FODMAPs) Foods to limit or avoid Some foods may worsen both IBS symptoms and Mounjaro side effects: Spicy foods (may worsen nausea and digestive discomfort) Alcohol (irritates the gut and can worsen dehydration) Caffeine in excess (stimulates gut motility unpredictably) Artificial sweeteners (particularly sorbitol and mannitol) When to speak to your GP While some digestive changes are expected when starting Mounjaro, certain symptoms warrant medical attention
Quercetin shows strong blocking effects on NLRP3 inflammasome activation
In the worst long-term cases of B12 deficiency, people also experience neurological problems
