A meta-analysis of 77 RCTs involving 50,820 patients with T2DM found that compared with placebo, lifestyle modification, or active anti-diabetic drugs, SGLT2is were associated with a significantly higher risk of genital infections (RR, 3.30
Patients losing more than 1.5 kg per week carry substantially higher lithogenic risk than slower losers, regardless of drug class
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This titration period helps minimize side effects overall for both medications
Focus on whole, nutrient-dense foods that support satiety and energy levels
*Correspondence: Gang Liu [email protected] These authors have contributed equally to this work This article was submitted to Animal Reproduction - Theriogenology, a section of the journal Frontiers in Veterinary Science ORCID: Shubin Li orcid.org/0000-0002-6865-9667 Jingyu Ren orcid.org/0000-0002-0048-3052 Wenqi Zhang orcid.org/0000-0003-4891-500X Yanfeng Dai orcid.org/0000-0001-7147-1748 Gang Liu orcid.org/0000-0002-5180-3765 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers