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In corneal epithelial cell injury of dry eye disease, impaired autophagic flux leads to accumulation of sequestosome 1 (SQSTM1), which upregulates ACSL4 to promote the insertion of iron-dependent lipid peroxidation

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If youre still unusually tired after a few weeks of consistent hydration and steadier eating, its worth checking other contributors (sleep, iron status, B12, vitamin D, thyroid) with your GP especially if you have dietary restrictions

A review of treatments for SIBO in 2022 found studies are still scarce and of low quality, limiting their clinical applicability