801 KMT2B promotes RFK transcription by upregulating H3 methylation levels, thus activating the TNF-/NOX2 pathway, promoting ferroptosis and aggravating myocardial infarction size
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However, their long life-span, penetration through the bloodbrain barrier (BBB) 13 , and high therapeutic doses may allow them to directly act on central nervous system GLP-1Rs 12 , thereby causing CNS-dependent side effects
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