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The recent meta-analyses indicated that in patients with high TMAO plasma level, the incidence of major adverse cardiovascular events was significantly higher compared with patients with low TMAO levels [67], and that all-cause mortality increased by 7.6% per each 10 mol/L increment of TMAO [68]
[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Tepes M., Gojkovic S., Krezic I., Zizek H., Madzar Z., Santak G., Batelja L., Milavic M., Sikiric S., Kocman I., et al
3.5 Subgroup analysis To address the considerable heterogeneity observed across studies, we performed subgroup analyses focusing on three confounding factors (animal species, treatment agents, model drugs and dosages), to identify the sources of heterogeneity for the five primary outcomes (AST, ALT, SOD, MDA, GSH)
Some of these potential benefits include: Despite containing only three amino acids, KPV appears capable of reproducing many of the beneficial anti-inflammatory effects associated with its parent hormone
The role of iron in host-microbiota crosstalk and its effects on systemic glucose metabolism
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