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Response: We note that APC 5192 does not currently have a two times rule violation in the final rule data

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It highlights the importance of publishing negative data.'' Further, biotechnology company Phosphagenics, which used the drug in an anti-cellulite cream BodyShaper, sold in major stores, revealed this week that it dumped the ingredient last November after 17 months because it was useless and incredibly expensive

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Pernicious anaemia , the autoimmune condition causing B12 malabsorption, may coexist with other autoimmune disorders, including autoimmune thyroid disease and, less commonly, rheumatoid arthritis

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