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Unlike Ozempic and Wegovy, which are solely glucagon-like peptide-1 (GLP-1) receptor agonists, or Mounjaro and Zepbound, which combine GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonism, retatrutide works by activating three key hormonal pathways

doi: 10.3389/fphar.2022.819470 [DOI] [PMC free article] [PubMed] [Google Scholar] 137.Teixeira LCR, Luizon MR, Gomes KB

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Individual results depend on factors including starting weight, dose, lifestyle changes, and adherence to treatment