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Lilly's retatrutide demonstrated significant weight loss in adults with obesity and knee osteoarthritis (TRIUMPH-4 topline results)

These limitations dont invalidate the positive safety findings but do suggest that comprehensive medical supervision remains appropriate for anyone using AOD-9604, particularly for off-label applications or extended treatment periods

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"People taking these drugs for obesity often describe a quieting of 'food noise,' the persistent preoccupation with food that drives overeating," Al-Aly said

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