Together with folate, cobalamins are essential cofactors required for DNA synthesis in cells where chromosomal replication and division are occurringmost notably the bone marrow and myeloid cells
The few human studies used varying protocols: intramuscular injections for knee pain, intravenous administration for safety assessment, and presumably other routes for interstitial cystitis
Each Serving (1 tablet) Contains: Vitamin B12 (as Hydroxocobalamin) 1mg 40,000%
References Chang, C.H., Tsai, W.C., Lin, M.S., Hsu, Y.H., Pang, J.H
Certain medications such as Metformin, H2-receptor antagonists including Zantac (Ranitidine), Tagamet(Cimetedine), Famotidine, Pepcid AC (Oral Pepcid), Axid AR (Nizatidine), Proton pump inhibitors (PPIs)including Prilosec (Omeprazole), Nexium (Esomeprazole), Prevacid (Lanzoprazole) and Antacids e.g:Gaviscon can also affect your ability to absorb vitamin B12
Wolf E, Hoeflich A, Lahm H