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Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised Phase 3 trial

Methylmalonic acid, if not properly handled by B 12 , remains in the myelin sheath, causing fragility

High intakes of vitamin B12 have been linked to a lower risk of depression, which can be a major cause of sleep disorders like insomnia

Reported side effects range from mild (headache, nausea, injection-site reactions) to serious (allergic reactions, kidney strain, infection)

For example, citrus fruits are known for being high in vitamin C, while leafy greens are an excellent source of vitamin K ( In addition to vitamins and minerals, foods contain other essential nutrients, including protein, healthy fats, and fiber all of which are needed for overall health and optimal bodily functioning ( Furthermore, plant-based foods, in particular, are rich in antioxidants and phytochemicals, two classes of compounds that are linked to benefits reduced inflammation and protection against chronic disease ( In contrast, supplements do not offer the same nutritional benefits

First, we examined PCA plots at day 15 and day 20 (Supplementary Fig