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Dehydration is one of the most common complicating factors in difficult early-phase experiences with this class of compound and is entirely preventable with a structured approach

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This mechanism leads to a reduction in hunger and, consequently, calorie intake, facilitating significant weight loss

These medications work very similarly to GLP-1 medications like Ozempic, except that they also mimic a gut hormone called glucose-dependent insulinotropic polypeptide (GIP)

The pull-throughs were done under fluoroscopy using a motorized puller to calibrate position, a manometric catheter with radio-opaque markings to correlate pressure locus with fluoroscopic landmarks, and endoclips located at the intragastric extreme of the EGJ and at the SCJ

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