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Download our GLP-1 app to Turn Your Weight Loss Journey into Your Favorite Game Summary Diarrhea is a recognized semaglutide side effect, appearing in about 10% of patients in a 2025 Bayesian network meta-analysis and 10.6% in at least one cohort, so this side effect is measurable rather than rare complaints

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This includes having a BMI of 30 or higher, or a BMI of 27 with an associated health condition such as type 2 diabetes, heart disease, or high blood pressure