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SCFAs also strengthen intestinal tight junctions, lowering metabolic endotoxemia and systemic inflammation while contributing to improved gutbrain axis signaling and central appetite regulation ( Omega-3 fatty acids represent another well-established category of nutraceuticals with broad metabolic benefits ( -oxidation, which can increase energy expenditure and reduce fat storage ( Collectively, these findings support the role of nutraceutical interventions, alone or in combination with lifestyle modifications, as a promising multifaceted approach to address not only weight control but also the inflammatory and metabolic disturbances underlying obesity

, John, P