There was a decline in composite symptom scores (81 to 63) alongside concurrent rises in quality of life (25 to 50) and working capacity (5 to 25) [103]
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These central nervous system effects translate to reduced caloric intake clinical trials show participants on semaglutide consume about 500-800 fewer calories per day without conscious effort or hunger

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WT mice was calculated for individual replicates, averaged, and converted to a log2 scale
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