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Many researchers choose to inject both on the same morning to maintain a consistent weekly schedule

Stabilize levels so you are less likely to swing between feeling better and then dipping again

Sag CM, Santos CXC, Shah AM

Human trials are shorter but show improvements in biological aging markers, inflammation levels, and cellular stress response [5]

Systemic vascular structure and function Though it remains unclear whether reductions in CBF or cerebral metabolism occurs first in the ADRD cascade, mechanical factors such as systemic and cerebral arterial stiffening are additional early stage vascular markers implicated in cerebral hypoperfusion in older adulthood beyond the typical effects of aging (Mitchell, 2011