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10.3390/molecules28207122 56 LiuH.HuangY.HuangM.WangM.MingY.ChenW.et al (2023b)

Study 3: Combination With Diet Independent work showed that NNMT inhibition plus a lean/low-fat diet accelerated weight and fat loss beyond diet alone, improved the lean-mass-to-body-weight ratio, and ameliorated obesity-linked liver pathologies

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For this study, the researchers took the study back to mice because humans are so long-lived that it makes studying any interventions direct effect on lifespan extremely difficult