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They should also be instructed about signs and symptoms that warrant dose adjustment or medical evaluation, including severe gastrointestinal side effects or other unusual symptoms that may indicate adverse reactions, as determined relevant by the prescribing clinician

Current evidence suggests GHK-Cu may provide moderate adjunctive benefits in pigmentation disorder management when combined with established treatments including hydroquinone, kojic acid, or laser therapies, rather than serving as a primary depigmenting agent

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[DOI] [PMC free article] [PubMed] [Google Scholar] 239.Xue M., Shafie A., Qaiser T., Rajpoot N.M., Kaltsas G., James S., Gopalakrishnan K., Fisk A., Dimitriadis G.K., Grammatopoulos D.K., et al