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Further investigations of inherent variations of the GIPR within the normal population reveal that the missense GIPR variant, rs1800437 (Glu354Gln) that results in diminished GIPR signalling, leads to lower BMD and increased risk of non-vertebral fractures in perimenopausal Danish women

Over time, most patients will regain all the weight they lost, or more, after discontinuing treatment, he says

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Actionable Tip: Do not self-diagnose or begin taking high-dose supplements without medical guidance