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One significant limitation of GHK-Cu is its short in vivo half-life of approximately 30 minutes in plasma, combined with the instability of the metal-peptide complex due to copper high reactivity

GABA, the main inhibitory neurotransmitter, supports sleep, mood, blood pressure, pain perception, and precise nerve function.27 28 Studies show that mice without hepatic GSH synthesis die within a month, highlighting the importance of GSH in critical processes like digestion, DNA replication, respiration, and muscle and nerve function

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Nonetheless, current clinical studies have not identified a clear association between the use of these medications and elevated oncogenic risk [107]

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