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Gong, Y., Chai, Y., Ding, J.-H., Sun, X.-L

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Dysbiosis, through the lack of appropriate immunoregulatory and barrier factors, such as, e.g., short-chain fatty acids, causes inappropriate activation of the immune system, resulting in epithelial inflammation, epithelial barrier damage and disease development [55, 57,58,59,60,61]

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The tight junctions between intestinal epithelial cells and the integrity of the mucus layer are essential for intestinal barrier function 59

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