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J Bone Miner Res 35(8):14151423 [DOI] [PubMed] [Google Scholar] 13.Herrou J, Mabilleau G, Lecerf JM, Thomas T, Biver E, Paccou J (2024) Narrative review of effects of Glucagon-Like Peptide-1 Receptor Agonists on bone health in people living with obesity

While many current weight-loss medicines target two hormone receptors, retatrutide works to activate three hormone receptors, making it a powerful new medicine for individuals looking to lose weight

It is also important to be aware that slowed gastric emptying can affect the absorption of some oral medicines, particularly those with a narrow therapeutic index (for example, certain thyroid medications or anticoagulants)

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Typically, our patients begin noticing weight loss and positive changes within the first few weeks of treatment

If a protocol is not producing the expected response, our guide on why retatrutide may not be working explores the common causes