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As no pregnancy or lactation data exist for retatrutide, women who are breastfeeding should not use it

Tell your healthcare provider if you are taking medicines to treat diabetes including insulin or sulfonylureas which could increase your risk of low blood sugar

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Cafeteria diet feeding has been reported to induce metabolic endotoxemia in rats 52

3.2 Interference with lipid metabolism Changes in gut microbiota among PCOS patients significantly influence lipid metabolism through various mechanisms (50)