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doi: 10.1186/1471-2458-9-88 21 YounossiZM

The FDA has never approved this combination, and cardiology literature documents increased rates of arrhythmias and hypertensive episodes in patients attempting dual therapy

During the median follow-up period of 20 months (ranging from 6 to 48 months), the incidence of MACEs was significantly lower in the GLP-1RA group (7.63%)compared to the control group (19.85%) (HR 0.444