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Organ tropism can be fine-tuned by altering nanocarrier lipid tail length, pKa, or incorporating selective organ targeting (SORT) motifs to redirect biodistribution away from hepatic default accumulation and toward extrahepatic sites such as adipose tissue or the CNS [461, 462]

10.1136/hrt.2010.219345

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Overall prescribing rates (GLP-1 RA prescriptions per total prescriptions) have remained stable in the last 3 months

Sewell AC, Bohles HJ

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