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CONTRAINDICATIONS BOOK NOW Contraindications & Precautions: Pregnant or Breastfeeding Women: Tirzepatide is contraindicated due to unestablished safety during pregnancy and lactation

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Beyond weight loss, retatrutide produces significant metabolic benefits: 30% reduction in triglycerides, 8% increase in HDL cholesterol, 7.4 mmHg decrease in systolic blood pressure, 50% reduction in liver fat, and improved glycemic control (HbA1c reduction of 0.4% even in non-diabetics)

The Mayo Clinic's guidance on GLP-1 medications also emphasizes gradual dose titration to improve tolerability

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